DuneCopasi within a computational electrophysiology pipeline allowing to solve the electrophysiological mono-domain equations with Mitchell-Schaefer cell model using a medical imaging derived from biventricular geometry (left) and mathematical modelling predicting that nuclear phosphorylation controls spatial localization of Hippo signalling pathway components YAP and TAZ (right) (Ospina De Los Ríos et al. 2024).